Surgeons in the Neuroscience Institute at Allegheny General Hospital are now using laser energy and MRI visualization to remove brain tumors that previously were difficult to access via other minimally-invasive surgical techniques.
"The radiation therapy fields now are much more precise, similar to a sniper. It becomes very important that we don’t cause any collateral damage because the bullet we’re using is a lot more powerful, but if it’s misdirected, it can cause a lot more damage.”
For the first time, doctors have breached the human brain's protective layer to deliver cancer-fighting drugs. The Canadian team used tiny gas-filled bubbles, injected into the bloodstream of a patient, to punch temporary holes in the blood-brain barrier.
A new treatment option at Baptist MD Anderson Cancer Center could help extend the life of newly diagnosed brain tumor patients. Patients diagnosed with glioblastoma multiforme now have an additional tool that works along with chemotherapy and radiation.
Canada’s medical researchers have found a breakthrough method to deliver chemotherapy drugs using a new ultrasound technique to breach the brain’s protective membrane and sneak past the stubborn blood-brain barrier.
The preliminary success of this research opens the door for treatment of other brain diseases that are normally hindered by the protection of the blood-brain barrier, including brain tumors, Alzheimer's disease, and many psychiatric conditions.
In a significant breakthrough, the Translational Genomics Research Institute (TGen) has identified a drug, propentofylline or PPF, that could help treat patients with deadly brain cancer.
Scientists have pioneered research evidencing the use of cerebrospinal fluid (CSF) as liquid biopsy for the potential prognosis, treatment, identification and tracking of brain tumor genomic alterations not only in real time but over time.
A team of Canadian scientists has done something completely extraordinary and has permeated the blood-brain barrier (BBB) inside of a living patient to administer chemotherapy medication.
Laser Ablation - the process enables surgeons to destroy brain tumors and lesions with pinpoint precision and allows patients to avoid conventional invasive surgery.
Scientists at Toronto’s Sunnybrook Hospital have taken the next bold step in chemotherapy by developing a non-invasive procedure to treat brain tumours.
Gamma Knife Perfexion, a technology that has been referred to as the “gold standard” treatment for non-invasive radiosurgery of the brain.
The first trial failed to reduce her tumor, but in January 2014, Rooney was enrolled in a second trial that shrunk her tumor from the size of a half dollar to dime size.
The time taken to diagnose brain tumours in children in this country has been slashed thanks to new guidelines from the University of Nottingham. The guidelines and a national awareness campaign have taken the UK from one of the worst ranking countries in the world to one of the best.
thromboDx, a molecular diagnostic company announced that a 283 subject study shows that its' blood platelet based diagnostic platform enables accurate detection, classification and subtyping of cancer in the equivalent of one drop of blood.
Federal health officials on Tuesday approved a first-of-a-kind drug that uses the herpes virus to infiltrate and destroy deadly skin cancer tumors.
Research is underway at Washington University to test a new approach to cancer treatment. Beyond traditional therapies like surgery, chemotherapy and radiation, scientists want to know if the human body's own immune system can attack tumors.
A new microscope, developed in the University's Medical School, could help surgeons with the difficult task of tumor removal by showing the difference between healthy and tumorous tissue in real-time.
Research into life-extending treatments for brain cancer patients has been taking a rare turn toward the hopeful, as trials of immunotherapy and tumor treating fields (TTF) are showing promise of beneficial results. - See more at: http://www.clinicaloncology.com/ViewArticle.aspx?d=Solid+Tumors&d_id=148&i=October+2015&i_id=1236&a_id=34003#sthash.MtNvMWjy.dpuf
Danish scientists at the University of Copenhagen and the University of British Columbia may have accidentally stumbled on to a discovery that could possibly be a game changer in the fight against cancer.
When Avi Yaron found out he had an inoperable brain tumor, he didn't take it lying down. Rather than accept that his life was over, he invented the technology that saved his life and is now saving the lives of thousands of others around the world.
But a new laser-based microscopic technology may help surgeons see the difference between tumor tissue and normal brain in real-time.
An imaging technology called MR spectroscopy is allowing doctors to diagnose brain tumors without putting patients through the rigors of a brain biopsy.
With more than 100 types of cancer, glioblastoma is one of the more aggressive forms of brain cancer, which can shorten life spans anywhere from two weeks to two years. To add months to a patient's life, doctors are trying a new treatment called Optune.
The U.S. Food and Drug Administration today approved an expanded indication for the Optune device to treat patients with newly-diagnosed glioblastoma multiforme (GBM), an aggressive form of brain cancer.
The Optune device uses NovoCure’s “tumor treating fields,” which use low-intensity, intermediate-frequency alternating electric fields that limit cancer cell replication and kill cancer cells.
A rabbit virus currently being developed for cancer therapy can be paired with one of several existing drugs to deliver a more potent punch to a deadly type of brain tumor cell, researchers have found.
The Optune device delivers low-intensity alternating electric fields to the brain. The procedure is disrupting cell division and killing cancer cells.
Scientists found that combining anticoagulant drugs and antidepressants can cause cancer cells to eat themselves and hinder the progression of the killer disease.
EPFL scientists have found that combining antidepressants with anticoagulants slows down brain tumors (gliomas) in mice.
OncoRx Pharmaceuticals, Inc. is announcing its launch as an early-stage pharmaceutical company focused on the development of drug therapies that control the progression of therapy-resistant malignant tumors.
Scientists and neurosurgeons are working together to build a huge bank of pediatric brain tumor samples to advance research and find cures.
A new article published in Neurology suggests that being overweight or obese may be linked to an increased risk of developing meningioma, a type of brain tumor.
Current drugs may stop working against the most common type of brain tumor in children, medulloblastoma, but the tumor could be targeted in a new way, according to Stanford University scientists.
In research to be published in the journal eLife, a team tested a drug in mice with a brain tumor that is resistant to Vismodegib, the drug in current use. The drug, normally used to treat inflammatory lung diseases, dramatically inhibited tumor growth from the first day of treatment.
An associate professor of epidemiology at the Ohio State University led a research that found changes in the immune function five years before patients were being diagnosed with glioblastoma.
A young Chicago Bears fan who named his brain tumor after Aaron Rodgers will get to attend the season opener against the Green Bay Packers on Sept. 13
NASA scientists are working with researchers at the Skull Base Institute in Los Angeles to develop a “super instrument,” an endoscope with a 3D camera that will allow neurosurgeons to better navigate brain tissue during tumor resections.
The first group of patients has completed their initial dose of a special nanotechnology delivery of radioactive fat particles that target cancer cells in the brain, leaving the healthy tissue mostly untouched.
A new treatment for glioblastoma could enter clinical trials following the results of a new mouse study that looked at the effects of chemotherapy agent decitabine combined with T cell immunotherapy.
Investigators have discovered that determining the tumor's subgroup can be achieved noninvasively, using magnetic resonance spectroscopy (MRS).
UCLA scientists have developed a potentially promising new combination therapy for glioblastoma, the most common and deadliest form of brain cancer.
A new laser-based tool would allow surgeons to tell cancer tissue from normal brain tissue at the microscopic level while they are operating and would avoid the problem of leaving behind cells that could spawn a new tumor.
A brain tumor is not always the death sentence many people think it is. "We have good techniques and it's not as dire as people think. From a neurosurgery standpoint, we have gotten pretty good at managing these patients with our arsenal of therapies and advances."
During an operation to remove a brain tumor for the first time in Europe, the researchers used the non-invasive technique, which measures light reflected off tissue to determine whether it is cancerous or healthy.
A young man has successfully undergone pioneering brain surgery. The procedure used two technologies - a laser probe and a smart knife - that appear set to revolutionize the performance of delicate surgery.
A study highlighting high-grade gliomas in children which found better survival rates with gross total resection (GTR), specifically in girls.
Doctors are treating former president Jimmy Carter's metastatic melanoma with a Keytruda, a combination of the latest immunotherapy drug and advanced radiation. It was just approved by the Food and Drug Administration last year and is the first of its kind.
A brain tumor patient was chosen to participate in an experimental treatment. She has to wear a head wrap for 24-hours a day. "It's supposed to send radio waves or something electrical to your brain that I can't feel, but it's supposed to keeping the tumors from growing," the patient said.
epidermal growth factor receptors (EGFR) promote tumor progression in many types of cancer.
Scientists at The University of Texas MD Anderson Cancer Center have shown that EGFR (epidermal growth factor receptors) may be shut down with the help of a cytokine known as MIF (macrophage migration inhibitory factor). It’s a finding they believe could signal a new way to look at treating tumors.
The doctors at the University Medical Center Utrecht asked Ambroz Bajec-Lapajne to sing in order to monitor his ability to vocalize and recognize the key change during the brain tumor surgery.
Drugs called ion channel blockers might prove useful in cancer therapy, according to research findings in fruit flies and mice by UC San Francisco scientists that led to unconventional treatment of a case of metastatic brain cancer.
Drugs called ion channel blockers, which are commonly used to treat cardiac, neurological, and psychiatric disorders, might prove useful in cancer therapy.
The experiments revealed that glioblastomas, described by medical experts as highly invasive brain tumors, take longer to spread when communication between the cells that comprise them is shut down.
The molecular makeup of brain tumors can be used to sort patients with gliomas into five categories, each with different clinical features and outcomes, researchers have shown. The finding could change the methods that physicians rely on to determine prognosis and treatment options.
Two Chemical Compounds Have Been Found Effective In Slowing Brain Cancer Cells
Many kids are addicted to "Frozen". There's no doubt about how popular "Frozen" is for kids and the sweetest thing a celebrity would do is to cheer up a lovely child with an illness in a "Frozen" way.
“Advances in particle therapy such as proton therapy as well as conventional x-ray therapy are allowing us to take a more targeted approach to halting tumor growth while sparing healthy tissue in an effort to preserve neurocognitive function.”
A team at Duke University is using a modified inactive polio virus to infect tumor cells, setting off an immune response that lasts for several months until often the tumor is gone for good.
A group of researchers from Johns Hopkins have developed an imaging technology that could provide surgeons with a color-coded map of a patient’s brain clearly indicating the cancerous and non-cancerous areas.
Two studies published in the New England Journal of Medicine (NJEM) have sought the aid of genetic mapping of brain tumors using next generation sequencing techniques.
It’s a high-tech alternative to the traditional surgery, which requires cracking open the skull and possibly manipulating the brain.
A Seattle biotech company that helps surgeons efficiently remove malignant brain tumors just made another important step toward bringing its main product to market.
A new noninvasive surgical procedure is showing great success at Emory-Saint Joseph’s Hospital for tricky brain surgeries and goes by the name of Gamma Knife.
After generating new brain tumor models, Cedars-Sinai scientists identified the role of a family of genes underlying tumor growth in a wide spectrum of high grade brain tumors.
Working in mice afflicted with glioblastoma, researchers used genetic material from the mice's tumors to "educate" their immune cells to recognize and attack the brain tumors.
Can we kill aggressive glioblastoma cells by making them “drink themselves to death”?
A small “keyhole” in the skull, nostrils, or behind the ear can sometimes provide a glimmer of hope for as many as 400,000 Americans who will experience cancer that spreads to the brain from other areas of the body.
A team of researchers has discovered that a previously unappreciated so-called long noncoding RNA mechanism controls tumor growth of Glioblastoma Multiforme cells.
There could be an additional option to treat brain tumors – a non-invasive device called “Optune” that could painlessly zap any remaining cancer cells.
Surgeons at the University of Kansas Hospital are implanting some tiny radioactive seeds.
The approach makes it possible to remove deeply embedded tumors through an opening as small as a dime, without damaging delicate brain tissue.
If he suddenly lost his ability to speak, that meant the area we stimulated in the brain was to be avoided during the surgery
With a turn of a safety key and a press of a “beam on” button, the radiation therapist sent positively charged protons through a series of powerful magnets, accelerating them to 60 percent of the speed of light, and focused them straight at the bottle cap-sized tumor in the brain.
It's a treatment that literally offers radiation from the inside out and a Kansas woman is one patient who received the first of it's kind procedure in the Midwest.
Optical coherence tomography (OCT) holds promise as a tool to guide surgeons as they operate on brain tumors, helping them to avoid removing healthy tissue.
Scott Baio’s wife, Renee Baio, has been diagnosed with a brain tumor, the Happy Days alum revealed on Facebook on Tuesday, June 16, via an emotional Facebook post.
Johns Hopkins researchers report they have developed an imaging technology that could provide surgeons with a color-coded map of a patient's brain showing which areas are and are not cancer.
Science fiction is meeting reality at Children’s Healthcare of Atlanta, where the pediatric hospital has become the first in the country to use a new exoskeleton in a pediatric rehabilitation environment.
A new clinical trial aims to help surgeons better identify and remove tumor cells from healthy brain tissue for safer curative outcomes in children.
The move to make cancer treatments gentler for children has paid a double dividend: More kids are surviving than ever before, and without the long-term complications that doomed many of their peers a generation ago.
Framing every scientific advancement in the cancer world as a “miracle cure” may attract readers, but the false hope it promotes does a disservice to patients.
The ability of many brain tumors to regenerate can be traced to cancer stem cells that evade treatment and spur the growth of new tumor cells.
Doctors can more effectively treat many brain tumors by first ascertaining their genetic characteristics, rather than studying tissue samples under a microscope, the standard practice.
The Medical College of Wisconsin is testing a laser-activated photosensitive dye as a new treatment for aggressive brain and spinal cord tumors.
Doctors say they kept Dias awake, singing and talking during his surgery, in order to monitor his motor functions and speech.
With the patient awake, doctors can keep tabs on cognitive functions while carefully operating on one of the most sensitive areas of the body. A wrong move could cause severe, and perhaps irreparable damage.
For adults with more aggressive glioblastomas who receive chemotherapy and radiation, the median survival is just over 14 months. In all, brain cancers kill nearly 14,000 Americans annually.
Between 1998 and 2014, there were 78 investigational brain tumor drugs that entered the clinical trial evaluation process. 75 failed, and only three (3) were approved (one conditionally). That is a 25:1 failure ratio in developing new brain tumor treatments over the past two decades.
A modified poliovirus therapy that is showing promising results for patients with glioblastoma brain tumors works best at a low dosage
The death of Joe Biden’s son from brain cancer sheds light on a disease that is alarmingly common in adults and routinely misunderstood.
Patients with small brain metastases from other tumor types should not routinely receive adjuvant whole brain radiation therapy (WBRT).
Improved tools and techniques in the operating room are offering very promising early results that may redefine what is “inoperable”.
By using data from models designed for individual patient's tumor growth patterns, doctors can improve decisions about treatment plans.
The University of Colorado Cancer Center and other institutions are reporting on promising results in clinical trials of the anti-cancer drug ONT-380 at the annual meeting.
Unlike biopsies that only look at a small part of the tumor in isolation, the atlas shows genes operating in their natural habitat.
Biomedical researchers have invented a tiny drug-delivery system that can identify cancer cell types in the brain through "virtual biopsies" and then attack the molecular structure of the disease.
Biomedical researchers at Cedars-Sinai have invented a tiny drug-delivery system that can identify cancer cell types in the brain through virtual biopsies and then attack the molecular structure of the disease.
By annotating the active genes and structures that make up glioblastoma tumors, researchers have created a roadmap for the deadliest form of brain cancer.
Magnetic stimulation (nTMS) has been gaining importance in neurosurgery. Among other applications, it is used to map brain tumors before an operation and to test whether important regions of the brain, for example motor and language areas, are affected.