UCLA scientists have developed a potentially promising new combination therapy for glioblastoma, the most common and deadliest form of brain cancer.
A new laser-based tool would allow surgeons to tell cancer tissue from normal brain tissue at the microscopic level while they are operating and would avoid the problem of leaving behind cells that could spawn a new tumor.
A brain tumor is not always the death sentence many people think it is. "We have good techniques and it's not as dire as people think. From a neurosurgery standpoint, we have gotten pretty good at managing these patients with our arsenal of therapies and advances."
During an operation to remove a brain tumor for the first time in Europe, the researchers used the non-invasive technique, which measures light reflected off tissue to determine whether it is cancerous or healthy.
A young man has successfully undergone pioneering brain surgery. The procedure used two technologies - a laser probe and a smart knife - that appear set to revolutionize the performance of delicate surgery.
A study highlighting high-grade gliomas in children which found better survival rates with gross total resection (GTR), specifically in girls.
Doctors are treating former president Jimmy Carter's metastatic melanoma with a Keytruda, a combination of the latest immunotherapy drug and advanced radiation. It was just approved by the Food and Drug Administration last year and is the first of its kind.
A brain tumor patient was chosen to participate in an experimental treatment. She has to wear a head wrap for 24-hours a day. "It's supposed to send radio waves or something electrical to your brain that I can't feel, but it's supposed to keeping the tumors from growing," the patient said.
epidermal growth factor receptors (EGFR) promote tumor progression in many types of cancer.
Scientists at The University of Texas MD Anderson Cancer Center have shown that EGFR (epidermal growth factor receptors) may be shut down with the help of a cytokine known as MIF (macrophage migration inhibitory factor). It’s a finding they believe could signal a new way to look at treating tumors.
The doctors at the University Medical Center Utrecht asked Ambroz Bajec-Lapajne to sing in order to monitor his ability to vocalize and recognize the key change during the brain tumor surgery.
Drugs called ion channel blockers might prove useful in cancer therapy, according to research findings in fruit flies and mice by UC San Francisco scientists that led to unconventional treatment of a case of metastatic brain cancer.
Drugs called ion channel blockers, which are commonly used to treat cardiac, neurological, and psychiatric disorders, might prove useful in cancer therapy.
The experiments revealed that glioblastomas, described by medical experts as highly invasive brain tumors, take longer to spread when communication between the cells that comprise them is shut down.
The molecular makeup of brain tumors can be used to sort patients with gliomas into five categories, each with different clinical features and outcomes, researchers have shown. The finding could change the methods that physicians rely on to determine prognosis and treatment options.
Two Chemical Compounds Have Been Found Effective In Slowing Brain Cancer Cells
Many kids are addicted to "Frozen". There's no doubt about how popular "Frozen" is for kids and the sweetest thing a celebrity would do is to cheer up a lovely child with an illness in a "Frozen" way.
“Advances in particle therapy such as proton therapy as well as conventional x-ray therapy are allowing us to take a more targeted approach to halting tumor growth while sparing healthy tissue in an effort to preserve neurocognitive function.”
A team at Duke University is using a modified inactive polio virus to infect tumor cells, setting off an immune response that lasts for several months until often the tumor is gone for good.
A group of researchers from Johns Hopkins have developed an imaging technology that could provide surgeons with a color-coded map of a patient’s brain clearly indicating the cancerous and non-cancerous areas.
Two studies published in the New England Journal of Medicine (NJEM) have sought the aid of genetic mapping of brain tumors using next generation sequencing techniques.
It’s a high-tech alternative to the traditional surgery, which requires cracking open the skull and possibly manipulating the brain.
A Seattle biotech company that helps surgeons efficiently remove malignant brain tumors just made another important step toward bringing its main product to market.
A new noninvasive surgical procedure is showing great success at Emory-Saint Joseph’s Hospital for tricky brain surgeries and goes by the name of Gamma Knife.
After generating new brain tumor models, Cedars-Sinai scientists identified the role of a family of genes underlying tumor growth in a wide spectrum of high grade brain tumors.
Working in mice afflicted with glioblastoma, researchers used genetic material from the mice's tumors to "educate" their immune cells to recognize and attack the brain tumors.
Can we kill aggressive glioblastoma cells by making them “drink themselves to death”?
A small “keyhole” in the skull, nostrils, or behind the ear can sometimes provide a glimmer of hope for as many as 400,000 Americans who will experience cancer that spreads to the brain from other areas of the body.
A team of researchers has discovered that a previously unappreciated so-called long noncoding RNA mechanism controls tumor growth of Glioblastoma Multiforme cells.
There could be an additional option to treat brain tumors – a non-invasive device called “Optune” that could painlessly zap any remaining cancer cells.
Surgeons at the University of Kansas Hospital are implanting some tiny radioactive seeds.
The approach makes it possible to remove deeply embedded tumors through an opening as small as a dime, without damaging delicate brain tissue.
If he suddenly lost his ability to speak, that meant the area we stimulated in the brain was to be avoided during the surgery
With a turn of a safety key and a press of a “beam on” button, the radiation therapist sent positively charged protons through a series of powerful magnets, accelerating them to 60 percent of the speed of light, and focused them straight at the bottle cap-sized tumor in the brain.
It's a treatment that literally offers radiation from the inside out and a Kansas woman is one patient who received the first of it's kind procedure in the Midwest.
Optical coherence tomography (OCT) holds promise as a tool to guide surgeons as they operate on brain tumors, helping them to avoid removing healthy tissue.
Scott Baio’s wife, Renee Baio, has been diagnosed with a brain tumor, the Happy Days alum revealed on Facebook on Tuesday, June 16, via an emotional Facebook post.
Johns Hopkins researchers report they have developed an imaging technology that could provide surgeons with a color-coded map of a patient's brain showing which areas are and are not cancer.
Science fiction is meeting reality at Children’s Healthcare of Atlanta, where the pediatric hospital has become the first in the country to use a new exoskeleton in a pediatric rehabilitation environment.
A new clinical trial aims to help surgeons better identify and remove tumor cells from healthy brain tissue for safer curative outcomes in children.
The move to make cancer treatments gentler for children has paid a double dividend: More kids are surviving than ever before, and without the long-term complications that doomed many of their peers a generation ago.
Framing every scientific advancement in the cancer world as a “miracle cure” may attract readers, but the false hope it promotes does a disservice to patients.
The ability of many brain tumors to regenerate can be traced to cancer stem cells that evade treatment and spur the growth of new tumor cells.
Doctors can more effectively treat many brain tumors by first ascertaining their genetic characteristics, rather than studying tissue samples under a microscope, the standard practice.
The Medical College of Wisconsin is testing a laser-activated photosensitive dye as a new treatment for aggressive brain and spinal cord tumors.
Doctors say they kept Dias awake, singing and talking during his surgery, in order to monitor his motor functions and speech.
With the patient awake, doctors can keep tabs on cognitive functions while carefully operating on one of the most sensitive areas of the body. A wrong move could cause severe, and perhaps irreparable damage.
For adults with more aggressive glioblastomas who receive chemotherapy and radiation, the median survival is just over 14 months. In all, brain cancers kill nearly 14,000 Americans annually.
Between 1998 and 2014, there were 78 investigational brain tumor drugs that entered the clinical trial evaluation process. 75 failed, and only three (3) were approved (one conditionally). That is a 25:1 failure ratio in developing new brain tumor treatments over the past two decades.
A modified poliovirus therapy that is showing promising results for patients with glioblastoma brain tumors works best at a low dosage
The death of Joe Biden’s son from brain cancer sheds light on a disease that is alarmingly common in adults and routinely misunderstood.
Patients with small brain metastases from other tumor types should not routinely receive adjuvant whole brain radiation therapy (WBRT).
Improved tools and techniques in the operating room are offering very promising early results that may redefine what is “inoperable”.
By using data from models designed for individual patient's tumor growth patterns, doctors can improve decisions about treatment plans.
The University of Colorado Cancer Center and other institutions are reporting on promising results in clinical trials of the anti-cancer drug ONT-380 at the annual meeting.
Unlike biopsies that only look at a small part of the tumor in isolation, the atlas shows genes operating in their natural habitat.
Biomedical researchers have invented a tiny drug-delivery system that can identify cancer cell types in the brain through "virtual biopsies" and then attack the molecular structure of the disease.
Biomedical researchers at Cedars-Sinai have invented a tiny drug-delivery system that can identify cancer cell types in the brain through virtual biopsies and then attack the molecular structure of the disease.
By annotating the active genes and structures that make up glioblastoma tumors, researchers have created a roadmap for the deadliest form of brain cancer.
Magnetic stimulation (nTMS) has been gaining importance in neurosurgery. Among other applications, it is used to map brain tumors before an operation and to test whether important regions of the brain, for example motor and language areas, are affected.
Alicante General Hospital has introduced new technology that helps to improve the survival of those patients with malignant brain tumors.
Cancer specialists at the hospital said it would drastically alter tumour treatment by offering them a way of targeting hard-to-reach tumours for patients unfit to undergo traditional surgery.
The work is noteworthy because the disease, a brain stem cancer called diffuse intrinsic pontine glioma, is nearly always fatal and lacks an effective treatment.
An international team of scientists found that the drug panobinostat and similar gene regulating drugs may be effective at treating diffuse intrinsic pontine gliomas (DIPG), an aggressive and lethal form of pediatric cancer.
Now, a new method of increasing radiation to the tumor is showing promise.
Treating brain tumors without traditional surgery. That's our focus of tonight's Ask the Doctor segment with Dr. Jonathan Tay who is the co-medical director of Reno CyberKnife.
Two studies showed that increasing the dose of radiotherapy given to children with an intracranial ependymoma can significantly improve their survival.
Researchers identified a promising combinatorial approach to treating glioblastomas, the most common form of primary brain cancer.
“This tumor is utilizing the core function of the brain, thinking, to promote its own growth,” says Michelle Monje, a researcher and neurologist at Stanford.
An international team of scientists found that the drug panobinostat (Farydak, Novartis) might be effective in treating diffuse intrinsic pontine glioma (DIPG), an aggressive and lethal form of brain cancer.
Phoenix researchers are studying one of the most deadly forms of brain cancer, and tests are narrowing down possible treatments.
A multicenter study has identified an FDA-approved medication that prolongs survival in mice with diffuse intrinsic pontine glioma, a brain tumor that now lacks chemotherapy treatments.
Thoughts can be deadly. So posits new research investigating the link between brain activity and tumor growth.
In the frightening world of brain tumors, “benign” is a good word to hear. But even a nonmalignant tumor can be dangerous.
Researchers have developed an “imageable” mouse model of brain-metastatic breast cancer and shown the potential of a stem cell-based therapy to eliminate metastatic cells from the brain and prolong survival.
Research provides deeper understanding of interactions between key factors in the insulin signaling pathway that influence the growth of glioblastomas.
... we have advanced surgical techniques and instrumentation which can make surgery safer and more effective.
Brain tumors are notoriously difficult for most drugs to reach, but Yale researchers have found an unlikely new ally against brain cancers — portions of a deadly virus similar to Ebola.
Scientists have managed to shrink one of the most aggressive brain cancers both in the lab and in mice by combining cannabinoids with radio therapy.
The 19-year-old college basketball player was memorialized with her own music & words in the arena where she had one of her greatest moments.
Marijuana can attack certain cancer cells and brain tumors, discover the US government-funded National Institute on Drug Abuse researchers, according to sputniknews.
Biologists have discovered a vulnerability of brain cancer cells that could be exploited to develop more-effective drugs against brain tumors.
Scientists have identified a small RNA molecule that can suppress cancer-causing genes in mice with glioblastoma mulitforme (GBM).
Malignant tumors contain stem cells, prompting worries among medical experts that the cells' transformative powers help cancers escape treatment.
Lauren Hill spent her final year bravely getting on the court and inspiring others to live fully. She succeeded at both.
The future is now, at least for Virginia Tech scientists who have come up with a way to visualize potential brain cancer treatments in real time.
Every once in a while, a story comes through 60 Minutes that has the potential to change lives.
By injecting a modified version of polio in two patients with glioblastoma brain tumors, a doctor has eliminated their tumors without infecting them with polio.
A laser pen can spot the subtle difference between the healthy and cancerous tissue.
New research finds a new approach to fight brain cancer holds promise – giving cancer a cold…a cold virus.
An experimental drug that attacks brain tumor tissue by crippling the cells' energy source has passed early tests in animal models and human tissue cultures.
Study found that patients with low-grade gliomas and at high risk for tumor recurrence have an overall survival of 73% after 3 years when treated with radiation plus temozolomide, a chemotherapy drug.
Proton beam therapy is a very precise pinpoint form of radiation therapy. This form of therapy is especially important for children because they are more susceptible to the side effects from the radiation therapy.
Successful treatment shows how precision medicine — tailoring therapy to each patient's genetic needs — is beginning to transform cancer care.
A new tool is allowing doctors better access to those hard-to-reach sections of the brain, using a minimally-invasive approach to remove lesions.
Treating brain tumors can be difficult, especially if they’re rare or are in a particularly complicated part of the brain. Now, a combination of technologies is helping to map out a better treatment.
David Williams is now the first human ever treated with a new type of radiation therapy that targets the center of his brain tumor.
New technology developed in San Antonio could possibly give brain cancer patients a second chance. The first human ever to try it is responding well to the treatment.
It is still very early in the research stages, but the work being done at University of Florida laboratory is showing promise that it could save the lives of many people living with brain cancer.
A study tested an innovative theory that a tetanus shot may increase the effectiveness of a vaccine used to treat lethal brain tumors, leading to improved patient survival.
I don't have an answer as to why I'm OK and my friend is gone, but I know it makes me push harder ...